Faslodex How it works, Uses, Side Effects, Interactions
Today’s Article about Faslodex How it works, Uses, Side Effects, Interactions
Benefits of using this medication
Fulvestrant belongs to the group of cancer-fighting medications called antineoplastics, and specifically to the type of antineoplastics known as antiestrogens. It treats certain types of breast cancer by blocking the effects of the hormone estrogen in the body. This prevents the growth of the types of breast cancer cells that require estrogen for growth and survival.
This medication may be available under several brands and/or in several different dosage forms. Any brand name of this medication may not be available in all of the dosage forms or approved for all of the conditions discussed in this article. As well, some forms of this medication may not be used for all of the conditions discussed in this article.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their physician has not prescribed it.
dosage forms of medication
Each mL of clear, colourless-to-yellow, viscous liquid for injection contains 50 mg of fulvestrant. Nonmedicinal ingredients: benzyl alcohol, benzyl benzoate, castor oil, and ethanol 96%.
dose of medication
Fulvestrant is available only as an injection into the muscle of the buttocks. When starting treatment, 500 mg is given as 2 injections of 250 mg, once every 2 weeks for 3 doses. After this, a dose is given every 28 days. Some people can be taught to give this medication to themselves. If this is the case, make sure you understand exactly how it is to be injected as instructed by your physician or nurse. The medication should be a clear, colourless-to-yellow, thick liquid. Do not use the medication if it appears cloudy or discoloured, or if there are particles floating in it.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your physician has recommended a dose different from the ones listed here, don’t change the way that you are taking the medication without consulting your physician.
It is important to use this medication exactly as prescribed by your physician.
in case of missed dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you aren’t sure what to do after missing a dose, contact your physician or pharmacist for advice.
Store this medication in its original package in the refrigerator, protect it from light, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Contraindications to the use of the medication
Do not use this medication if you:
- are allergic to fulvestrant or any ingredients of the medication
- are breast-feeding
- are pregnant
side effects of the medication
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below aren’t experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your physician.
These symptoms may occur in some patients and in this case, you should refer to your consultant. But the majority of the patients don’t suffer from any side effects, so do not stop using the medicine because of fear of in listed side effect . , .
Contact your physician if you experience these side effects and intolerable. Your pharmacist may be able to advise you on managing side effects.
- hot flashes
- loss of appetite
- mild pain, redness, or swelling around the site of the injection
Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you don’t seek medical attention.
Check with your physician as soon as possible if any of the following side effects occur:
- signs of a bladder infection (frequent urination, pain or burning feeling when urinating, smelly urine)
- signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
Stop taking the medication and seek immediate medical attention if any of the following occur:
- signs of an allergic reaction (hives; difficulty breathing; swelling of the face, tongue, or throat)
Some people may experience side effects other than those listed. Check with your physician if you notice any symptom that worries you while you are taking this medication.
precautions of the medication
Before you start using a medication, be sure to inform your physician of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
HEALTH CANADA ADVISORY
October 18, 2016
Health Canada has issued new restrictions concerning the use of Faslodex (fulvestrant). To read the full Health Canada Advisory, visit Health Canada’s web site at www.hc-sc.gc.ca.
Driving: This medication usually doesn’t make you drowsy or impair your ability to drive or operate machinery. However, it may make some people feel weak. Do not drive or operate machinery if you feel weak.
Kidney function: People with kidney problems or poor kidney function should be closely monitored by their physician while taking this medication.
Lab test results: Fulvestrant can cause falsely high amounts of estradiol (a type of estrogen) in blood tests. This can lead to misinterpretation of whether you are premenopausal or postmenopausal. Make sure all the medical professionals involved in your care know you are taking this medication.
Liver disease: Fulvestrant may reduce liver function and can cause liver failure. Liver disease or reduced liver function may cause this medication to build up in the body, causing side effects. If you have liver problems, discuss with your physician how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your physician immediately.
Risk of bleeding: Because this medication is given by intramuscular (IM) injection, people with an increased risk of bleeding, such as those taking blood thinners (e.g., warfarin) or those with medical conditions that can cause bleeding, should take extra care when giving themselves an injection.
Pregnancy: This medication should not be used during pregnancy. It may cause severe harm to the developing baby if it is used by the mother during children. If you become pregnant while taking this medication, contact your physician immediately.
Breast-feeding: It isn’t known if fulvestrant passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your physician about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children.
Drug-Drug interaction of the medication
Tell your physician or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them. Depending on your specific circumstances, your physician may want you to:
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
An interaction between two medications doesn’t always mean that you must stop taking one of them. talk to your physician about how any drug interactions are being managed or should be managed.
Terms and Definitions used in this article:
side effects: The drug side effects are monitored by Clinical Trials and studies that are regularly published in scientific journals and medical conferences.
- If an adverse effect occurred during a clinical trial, whether it was relevant or irrelevant to the drug. It should be registered as a side effect.
- The medicine is not registered for use if the side-effects are dangerous or life-threating, and the approval of drug release to the Market is regulated by the World Health Organization WHO, the Food and Drug Administration of the United States FDA, EMEA and other national ministry of health.
- These symptoms may occur in some patients and in this case, you should refer to your consultant. But the majority of the patients don’t suffer from any side effects, so do not stop using the medicine because of fear of in listed side effect
Contraindications to the use of the drug:
contraindication is a condition or factor that serves as a reason to withhold a certain medical treatment due to the harm that it would cause the patient. Contraindication is the opposite of indication, which is a reason to use a certain treatment.
Therefore, you must inform your doctor of all the diseases that you suffer from and your health history in order not to be affected negatively by the use of a particular medicine and please do not stop using the medication by yourself without referring to a doctor
is a change in the action or side effects of a drug caused by concomitant administration with a food, beverage, supplement, or another drug.
There are many causes of drug interactions. For example, one drug may alter the pharmacokinetics of another. Alternatively, drug interactions may result from competition for a single receptor or signaling pathway.
- US National Library of Medicine, National Institutes of Health
- Centers for Disease Control and Prevention
- The FDA‘s website
- WHO‘s website
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