Dysport How it works, Uses, Side Effects, Interactions
Today’s Article about Dysport How it works, Uses, Side Effects, Interactions
Benefits of using this medication
Botulinum toxin is classified as neuromuscular paralytic agents. It blocks the nerves that are responsible for muscle activity. For cosmetic purposes, it can be used to smooth out facial lines and wrinkles, such as those that form between the eyebrows, on the forehead, and around the eyes (crow’s feet). It gives skin a smoother appearance by relaxing the muscles in the area where it was injected. It may also be used to treat cervical dystonia, also known as spasmodic torticollis, a condition in which the muscles of the neck stay in a state of contraction, and to treat focal spasticity of the upper and lower limbs. This medication is also used for the treatment of lower limb spasticity in children 2 years of age and older.
This medication may be available under several brands and/or in several different dosage forms. Any brand name of this medication may not be available in all of the dosage forms or approved for all of the conditions discussed in this article. As well, some forms of this medication may not be used for all of the conditions discussed in this article.
dosage forms of medication
Each sterile vial contains 300 units of lyophilized abobotulinumtoxinA. Nonmedicinal ingredients: human serum albumin and lactose.
Each sterile vial contains 500 units of lyophilized abobotulinumtoxinA. Nonmedicinal ingredients: human serum albumin and lactose.
dose of medication
The dose of medication required depends on the area being treated and individual circumstances.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your physician has recommended a dose different from the ones listed here, don’t change the way that you are receiving the medication without consulting your physician.
Botulinum toxin is available in injectable form. The injection will be given into a muscle by a qualified health care professional.
It is important to receive this medication exactly as recommended by your physician. If you miss an appointment to receive botulinum toxin type A (cosmetic), contact your physician as soon as possible to reschedule your appointment. It is very important to keep your appointments for treatment and follow-up.
Before mixing, this medication is stored in the refrigerator and protected from light. Once mixed, it can be stored for up to 24 hours in the refrigerator.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Contraindications to the use of the medication
Do not use botulinum toxin type A (Dysport) if you:
- are allergic to botulinum toxin or to any of the ingredients of the medication
- are allergic to cow’s milk protein
- have an infection at the site the injection is to be given in
- have myasthenia gravis, amyotrophic lateral sclerosis, or Eaton Lambert syndrome
side effects of the medication
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below aren’t experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your physician.
These symptoms may occur in some patients and in this case, you should refer to your consultant. But the majority of the patients don’t suffer from any side effects, so do not stop using the medicine because of fear of in listed side effect . , .
Contact your physician if you experience these side effects and intolerable. Your pharmacist may be able to advise you on managing side effects.
- drooping of the upper eyelid
- face pain
- flu-like illness
- general feeling of being unwell
- muscle aches
- muscle weakness at the injection site
- pain, tenderness or bruising, burning, swelling, or stinging at the injection site
- redness of the skin
- stuffy nose
- tightness of the skin
Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you don’t check with your physician or seek medical attention.
Check with your physician as soon as possible if any of the following side effects occur:
- abnormal heart rhythm
- blurred or decreased vision
- burning or prickling sensation
- facial paralysis
- itchy skin
Stop taking the medication and seek immediate medical attention if any of the following occur:
- breathing problems
- difficulty swallowing
- speech problems
- symptoms of a severe allergic reaction (e.g., hives, difficulty breathing, swelling of the throat or mouth)
Some people may experience side effects other than those listed. Check with your physician if you notice any symptom that worries you while you are taking this medication.
precautions of the medication
Before you start using a medication, be sure to inform your physician of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Distant toxin spread: Very rarely, this medication may spread to other parts of the body other than where it was injected, leading to muscle weakness, difficulty swallowing, pneumonia, speech difficulties, and breathing problems. Distant toxin spread can be fatal. If you develop severe difficulty swallowing, speaking, or breathing while using this medication, contact your physician immediately. This medication should be used with caution in people who have pre-existing swallowing, breathing, or nerve problems.
Heart problems: There have been rare reports of heart problems such as irregular heart rhythms and heart attack following injection of this medication. If you have heart disease discuss with your physician how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Other medical conditions: People with amyotrophic lateral sclerosis, with disorders that produce a depletion of acetylcholine, or disorders that produce peripheral neuromuscular dysfunction should discuss with their physician how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Pregnancy: This medication should be used during pregnancy only if the potential benefit justifies the potential risk to the mother and unborn baby. If you become pregnant while using this medication, contact your physician immediately.
Breast-feeding: It isn’t known if this medication passes into breast milk. If you are a breast-feeding mother and are using this medication, it may affect your baby. Talk to your physician about whether you should continue breast-feeding.
Children: The safety and effectiveness of this medication have not been established for children under the age of 18, except for the treatment of lower limb spasticity in children over the age of 2 years.
Drug-Drug interaction of the medication
There may be an interaction between botulinum toxin type A (Dysport) and any of the following:
- aminoglycoside antibiotics (e.g., gentamicin, neomycin, tobramycin, streptomycin)
- antihistamines (e.g., brompheniramine, diphenhydramine)
- antipsychotics (e.g. clozapine, olanzapine, risperidone)
- muscle relaxants (e.g. cyclobenzaprine, orphenadrine)
- polymyxins (e.g., polymyxin B)
- tricyclic antidepressants (e.g., amitriptyline, clomipramine, imipramine)
If you are taking any of these medications, talk to your physician or pharmacist. Depending on your specific circumstances, your physician may want you to:
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
An interaction between two medications doesn’t always mean that you must stop taking one of them. talk to your physician about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your physician or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Terms and Definitions used in this article:
side effects: The drug side effects are monitored by Clinical Trials and studies that are regularly published in scientific journals and medical conferences.
- If an adverse effect occurred during a clinical trial, whether it was relevant or irrelevant to the drug. It should be registered as a side effect.
- The medicine is not registered for use if the side-effects are dangerous or life-threating, and the approval of drug release to the Market is regulated by the World Health Organization WHO, the Food and Drug Administration of the United States FDA, EMEA and other national ministry of health.
- These symptoms may occur in some patients and in this case, you should refer to your consultant. But the majority of the patients don’t suffer from any side effects, so do not stop using the medicine because of fear of in listed side effect
Contraindications to the use of the drug:
contraindication is a condition or factor that serves as a reason to withhold a certain medical treatment due to the harm that it would cause the patient. Contraindication is the opposite of indication, which is a reason to use a certain treatment.
Therefore, you must inform your doctor of all the diseases that you suffer from and your health history in order not to be affected negatively by the use of a particular medicine and please do not stop using the medication by yourself without referring to a doctor
is a change in the action or side effects of a drug caused by concomitant administration with a food, beverage, supplement, or another drug.
There are many causes of drug interactions. For example, one drug may alter the pharmacokinetics of another. Alternatively, drug interactions may result from competition for a single receptor or signaling pathway.
- US National Library of Medicine, National Institutes of Health
- Centers for Disease Control and Prevention
- The FDA‘s website
- WHO‘s website
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