Today’s Article about Locacorten Vioform Cream How it works, Uses, Side Effects, Interactions
Benefits of using this medication
This combination product contains two medications: clioquinol and flumethasone. Clioquinol is an anti-infective agent that fights bacteria and fungi. Flumethasone has an anti-inflammatory and anti-itching effect and belongs to the family of drugs called corticosteroids.
This combination of ingredients is used for the relief of inflammation and itching due to skin conditions such as contact or allergic dermatitis (eczema) or seborrheic dermatitis, which also have bacteria or fungus infecting the skin. The cream is slightly drying to the skin and is useful for moist, weeping wounds and in the folds of the skin.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their physician has not prescribed it.
dosage forms of medication
Each tube of off-white, water-soluble cream contains 3% clioquinol and 0.02% flumethasone. Nonmedicinal ingredients: cetyl alcohol, cetyl palmitate, glycerin, petrolatum, phenoxyethanol, sodium lauryl sulfate, stearyl alcohol, and water.
dose of medication
The recommended dose is one thin application 2 or 3 times daily.
Do not apply this medication near the eyes and don’t use this cream under dressings that don’t breathe unless instructed to do so by your physician.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your physician has recommended a dose different from the ones listed here, don’t change the way that you are taking the medication without consulting your physician.
Flumethasone – clioquinol cream should not be applied to open wounds or sores.
Avoid getting any cream in the eyes. If the medication gets into your eyes accidentally, flush them at once with plenty of water.
This medication usually begins to work within the first few doses. Be sure to use the medication for the prescribed amount of time, even if the problem seems to have cleared, so that the infection won’t come back.
If there is no improvement in the skin condition after a week, or if the condition appears to be worsening, stop using the medication and contact your physician.
This medication may turn yellow when it is exposed to air. This is normal and the cream is still safe to use.
Staining may occur to skin, nails, hair, or fabric with the use of this medication.
It is important to use this medication exactly as prescribed by your physician. in case of missed dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for a missed one. If you aren’t sure what to do after missing a dose, contact your physician or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Contraindications to the use of the medication
Flumethasone – clioquinol cream should not be used by or given to anyone who:
- is allergic to clioquinol, flumethasone pivalate, or any ingredients of the medication
- is allergic to corticosteroids, hydroxyquinolines or quinolone derivatives
- is under 2 years of age
- has open wounds or ulcerated areas on the skin
- has pre-existing tuberculosis of the skin, or viral infections of the skin (e.g., chickenpox, skin eruptions following vaccination, herpes simplex, herpes zoster)
- has rosacea, acne vulgaris, or dermatitis around the mouth
side effects of the medication
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below aren’t experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your physician.
These symptoms may occur in some patients and in this case, you should refer to your consultant. But the majority of the patients don’t suffer from any side effects, so do not stop using the medicine because of fear of in listed side effect . , .
Contact your physician if you experience these side effects and intolerable. Your pharmacist may be able to advise you on managing side effects.
- burning, dryness, irritation, itching, or redness or skin (usually mild and temporary)
- change in skin colour
- increased redness or scaling of skin sores (usually mild and temporary)
- skin rash (usually mild and temporary)
- yellow staining of the skin, nails, hair, or fabrics
Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you don’t seek medical attention.
Check with your physician as soon as possible if any of the following side effects occur:
- acne blood-containing blisters on skin
- burning and itching of skin
- increased skin sensitivity
- lack of healing of skin condition
- numbness in fingers
- painful, red or itchy, pus-containing blisters in hair follicles
- raised, dark-red, wart-like spots on skin, especially when medication is used on the face
- new or spreading skin infection
- thinning of skin with easy bruising
Some people may experience side effects other than those listed. Check with your physician if you notice any symptom that worries you while you are taking this medication.
precautions of the medication
Before you start using a medication, be sure to inform your physician of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Absorption: When flumethasone is used over extensive areas for prolonged periods and under dressings that don’t breathe, it is possible that enough medication will absorb into the bloodstream to cause side effects. talk to your physician about when you should stop using the cream.
Prolonged use of the cream over large areas of the body or applying it under dressings that don’t breathe could cause this medication to be absorbed into the bloodstream, potentially producing effects similar to those seen after taking corticosteroid medications by mouth for long periods of time.
Effectiveness of medication: Although the side effects associated with the use of this medication are uncommon and not to be expected from ordinary use, sensitization, irritation, and failure to produce improvement have been noticed in rare instances. If your condition doesn’t improve after one week of using the cream, call your physician.
Eyes: Use this medication with caution on lesions close to the eye. Take care to ensure that it doesn’t enter the eye, as glaucoma may result. Cataracts have been reported following internal use of corticosteroids.
Kidney function: If you have reduced kidney function or kidney disease, discuss with your physician how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Laboratory tests: This medication may interfere with the results of certain thyroid function tests and tests for phenylketonuria.
Liver function: If you have reduced liver function or liver disease, discuss with your physician how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Medical treatment: Be sure to tell all health professionals involved in your care that you are using this medication.
Thinning of skin: Using topical corticosteroid medications for a long period of time can cause skin to thin or soften or cause stretch marks. Your physician may recommend you stop using this medication once in a while or to apply to one area of the body at a time.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while using this medication, contact your physician immediately.
Breast-feeding: It isn’t known if flumethasone – clioquinol cream passes into breast milk. If you are a breast-feeding mother and are using this medication, it may affect your baby. Talk to your physician about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children less than 2 years old.
Drug-Drug interaction of the medication
There may be an interaction between flumethasone – clioquinol and any of the following:
- topical medications that contain corticosteroids
- topical medications that irritate the skin
If you are taking any of these medications, talk to your physician or pharmacist. Depending on your specific circumstances, your physician may want you to:
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
An interaction between two medications doesn’t always mean that you must stop taking one of them. talk to your physician about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your physician or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Terms and Definitions used in this article:
side effects: The drug side effects are monitored by Clinical Trials and studies that are regularly published in scientific journals and medical conferences.
- If an adverse effect occurred during a clinical trial, whether it was relevant or irrelevant to the drug. It should be registered as a side effect.
- The medicine is not registered for use if the side-effects are dangerous or life-threating, and the approval of drug release to the Market is regulated by the World Health Organization WHO, the Food and Drug Administration of the United States FDA, EMEA and other national ministry of health.
- These symptoms may occur in some patients and in this case, you should refer to your consultant. But the majority of the patients don’t suffer from any side effects, so do not stop using the medicine because of fear of in listed side effect
Contraindications to the use of the drug:
contraindication is a condition or factor that serves as a reason to withhold a certain medical treatment due to the harm that it would cause the patient. Contraindication is the opposite of indication, which is a reason to use a certain treatment.
Therefore, you must inform your doctor of all the diseases that you suffer from and your health history in order not to be affected negatively by the use of a particular medicine and please do not stop using the medication by yourself without referring to a doctor
is a change in the action or side effects of a drug caused by concomitant administration with a food, beverage, supplement, or another drug.
There are many causes of drug interactions. For example, one drug may alter the pharmacokinetics of another. Alternatively, drug interactions may result from competition for a single receptor or signaling pathway.
- US National Library of Medicine, National Institutes of Health
- Centers for Disease Control and Prevention
- The FDA‘s website
- WHO‘s website
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